NEW PERSPECTIVES IN GLIOBLASTOMA ANTIANGIOGENIC THERAPY

New perspectives in glioblastoma antiangiogenic therapy

Glioblastoma (GB) is highly vascularised tumour, known to exhibit enhanced infiltrative Dome Cameras potential.One of the characteristics of glioblastoma is microvascular proliferation surrounding necrotic areas, as a response to a hypoxic environment, which in turn increases the expression of angiogenic factors and their signalling pathways (RAS/R

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Measuring circularity from buildings to neighbourhoods

The circular economy (CE) aims to eliminate the concept of pollution and waste generation, maintain the integrity of the product over several use cycles, and focus on closing material and energy loops.Circularity metrics are relevant for monitoring, reporting and communicating CE implementation progress.Applied to buildings, these metrics deliver s

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Arthropathy and proteinuria: nail-patella syndrome revisited

[english] Nail-patella syndrome (NPS) is a pleiotropic autosomal-dominant disorder due to mutations in the gene LMX1B.It has traditionally been characterized by a tetrad of dermatologic and musculoskeletal abnormalities.However, one of the most serious manifestations of NPS is kidney disease, Accessories which may be present in up to 40% of affecte

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